Wade missed six of the Heat's past eight games because of the knee, which he initially injured a month ago but has aggravated twice since then.
"The most important thing is to be healthy," Wade told reporters Sunday. "So when I feel it, then I'll get back on the court. Obviously, I want to play. But I have to make sure that I'm right. You have to get healthy."
The playoffs are scheduled to begin April 20.
Wade's injury seems to be the most serious of the health issues that have affected Miami's three stars.
LeBron James sat out three games before he returned Saturday from a hamstring injury.
Chris Bosh missed Saturday's game with a hyperextended right knee and said he wasn't sure when he would return.
Heat coach Erik Spoelstra said Saturday that all three will be considered day to day for the rest of the regular season.